The Duke University Medical Center Pediatric Blood & Marrow Transplant Program expansion combined renovation and new facility development to support both patient care and GMP manufacturing. The project included a new manufacturing facility alongside specialized isolation rooms and treatment areas serving an immunocompromised patient population. WorkingBuildings, a Trinity Consultants team, provided comprehensive GMP consulting focused on the design, construction, and qualification of a fully GMP-compliant environment, with close attention to the HVAC, life safety, and critical power systems supporting these highly controlled spaces.